Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Medication for pain relief, constipation, heartburn__6154-both_sexes-4 |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_pos |
| GeneSet | CL21442, CANONICAL AND NON-CANONICAL NOTCH SIGNALING, AND FRINGE |
| Enrichment Score (ES) | 0.6397336 |
| Normalized Enrichment Score (NES) | 1.3147831 |
| Nominal p-value | 0.029087262 |
| FDR q-value | 0.29006848 |
| FWER p-Value | 0.692 |
| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | HES5 | 89 | 2.631 | 0.1848 | Yes |
| 2 | MAML3 | 538 | 1.675 | 0.2807 | Yes |
| 3 | MAML1 | 736 | 1.519 | 0.3793 | Yes |
| 4 | LFNG | 868 | 1.432 | 0.4754 | Yes |
| 5 | JAG2 | 1089 | 1.299 | 0.5569 | Yes |
| 6 | DLL3 | 2057 | 0.913 | 0.5692 | Yes |
| 7 | NOTCH1 | 2358 | 0.838 | 0.6130 | Yes |
| 8 | HEY2 | 2832 | 0.734 | 0.6397 | Yes |
| 9 | NOTCH4 | 4923 | 0.454 | 0.5567 | No |
| 10 | MFNG | 5303 | 0.423 | 0.5662 | No |
| 11 | DTX1 | 5662 | 0.395 | 0.5749 | No |
| 12 | HEY1 | 5734 | 0.389 | 0.5990 | No |
| 13 | NOTCH2 | 8165 | 0.246 | 0.4822 | No |
| 14 | NRARP | 10491 | 0.162 | 0.3651 | No |
| 15 | MAML2 | 10637 | 0.157 | 0.3684 | No |
| 16 | RFNG | 10813 | 0.152 | 0.3697 | No |
| 17 | HEYL | 12057 | 0.121 | 0.3096 | No |
| 18 | JAG1 | 12834 | 0.102 | 0.2740 | No |
| 19 | RBPJ | 13271 | 0.093 | 0.2566 | No |
| 20 | HES1 | 15616 | 0.053 | 0.1306 | No |
| 21 | DLL1 | 16075 | 0.045 | 0.1085 | No |
| 22 | DNER | 16382 | 0.036 | 0.0941 | No |
| 23 | NOTCH3 | 16570 | -0.000 | 0.0838 | No |
| 24 | DLL4 | 16987 | -0.000 | 0.0607 | No |
